Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 13/20 | 0.61 |
| ▸ | MAP4K3 | Q8IVH8 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650130 | 0.93 | MET (0.52) | METMAP4K3JAK2MAP4K4IGF1R | |
| SCHEMBL27630067 | 0.93 | MET (0.65) | METMAP4K3JAK2MAP4K4 | |
| SCHEMBL27650146 | 0.89 | MET (0.60) | METMAP4K3JAK2MAP4K4 | |
| SCHEMBL27629940 | 0.87 | MET (0.48) | METMAP4K3JAK2MAP4K4 | |
| SCHEMBL27630170 | 0.85 | MET (0.59) | METMAP4K3JAK2MAP4K4 | |
| SCHEMBL27630206 | 0.85 | MET (0.59) | METMAP4K3MAP4K4 | |
| SCHEMBL27630208 | 0.84 | MET (0.71) | METMAP4K3JAK2 | |
| SCHEMBL488145 | 0.84 | MET (0.68) | METMAP4K3JAK2MAP4K4MEN1 | |
| SCHEMBL27630103 | 0.83 | MET (0.50) | METMAP4K3JAK2MAP4K4 | |
| SCHEMBL30453384 | 0.82 | MET (0.84) | METMAP4K3JAK2MAP4K4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | claimed |