Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 16/20 | 0.71 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27650094 | 0.84 | MET (0.61) | METJAK2MAP4K3 | |
| SCHEMBL487774 | 0.83 | MET (1.00) | METCSF1RALK | |
| SCHEMBL30452699 | 0.83 | MET (1.00) | METCSF1RALK | |
| SCHEMBL488321 | 0.83 | MET (1.00) | METCSF1RALK | |
| SCHEMBL6417569 | 0.83 | MET (1.00) | METCSF1RALK | |
| SCHEMBL30452532 | 0.83 | MET (1.00) | METCSF1RALK | |
| SCHEMBL27630067 | 0.78 | MET (0.65) | METCSF1RJAK2MAP4K3 | |
| SCHEMBL27650130 | 0.78 | MET (0.52) | METJAK2MAP4K3 | |
| SCHEMBL487952 | 0.77 | MET (1.00) | METCSF1RALK | |
| SCHEMBL489386 | 0.77 | MET (1.00) | METCSF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |