Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 11/20 | 0.51 |
| ▸ | MAP4K3 | Q8IVH8 | 3/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.39 |
| ▸ | FYN | P06241 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630123 | 0.93 | MET (0.51) | METMAP4K3MAP4K4 | |
| SCHEMBL27629997 | 0.90 | MET (0.61) | METMAP4K3MAP4K4 | |
| SCHEMBL27630103 | 0.85 | MET (0.50) | METMAP4K3MAP4K4 | |
| SCHEMBL27629874 | 0.83 | MET (0.50) | METMAP4K3MAP4K4 | |
| SCHEMBL27629940 | 0.83 | MET (0.48) | METMAP4K3MAP4K4 | |
| SCHEMBL27650130 | 0.79 | MET (0.52) | METMAP4K3MAP4K4 | |
| SCHEMBL27630145 | 0.79 | MET (0.47) | METMAP4K3MAP4K4 | |
| SCHEMBL27630206 | 0.79 | MET (0.59) | METMAP4K3MAP4K4 | |
| SCHEMBL10217651 | 0.78 | MET (0.58) | METMAP4K3 | |
| SCHEMBL27629915 | 0.78 | MET (0.59) | METMAP4K3MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1777427-A | Aminoheteroaryl compounds as protein kinase inhibitors | SUGEN INC (US) | 2006-05-24 | — | — | CN | disclosed |