Tert-Butylbenzene

Tert-Butylbenzene

SCHEMBL27650352

C#C.CC(C)(C)c1ccccc1

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.50
TSHR P16473 4/20 0.48
ALDH1A1 P00352 5/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ALOX15 P16050 1/20 0.46
LMNA P02545 1/20 0.46
TYR P14679 1/20 0.46
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
CYP3A4 P08684 1/20 0.44
KCNN4 O15554 3/20 0.43
MAPT P10636 2/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
BCHE P06276 1/20 0.41
ACHE P22303 1/20 0.41
NPC1 O15118 1/20 0.41
RECQL P46063 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylbenzene SCHEMBL28820048 0.97 MAPK1 (0.48) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL22264597 0.94 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL337648 0.94 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL22264599 0.94 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL2568053 0.94 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL18889 0.94 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL27419202 0.91 MAPK1 (0.48) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL11852689 0.90 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL5921915 0.90 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1ALOX15
Tert-Butylbenzene SCHEMBL975494 0.90 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115838382-A Synthesis method of beta-ketophosphoric oxide 惠州学院 2023-03-24 CN claimed
CN-114507121-A Preparation method and product of alpha-alkenyl-alpha, alpha-difluoroaryl ketone compound 南京工业大学 2022-05-17 CN claimed
CN-107698435-B Application of ionic iron (III) complex in the carboxylation reaction of catalysis terminal alkyne compound and carbon dioxide 苏州大学 2019-09-10 CN claimed
CN-108530863-A A kind of corrosion-resistant compression-resistant material in deck 浙江新乐造船股份有限公司 2018-09-14 CN claimed
CN-107935801-A A kind of new method for synthesizing propargylamine class compound 湖南大学 2018-04-20 CN claimed
CN-107698435-A Application of ionic iron (III) complex in the carboxylation reaction of catalysis terminal alkyne compound and carbon dioxide 苏州大学 2018-02-16 CN claimed
CN-105585473-B Method for preparing propiolic acid compound 苏州大学 2017-11-28 CN claimed
CN-107353194-A A kind of preparation method of propine acid compounds 大连理工大学 2017-11-17 CN claimed
CN-105061372-B A kind of synthetic method of aphthofurans class compound 湖南大学 2017-06-20 CN claimed
CN-106674101-A Method for constructing quinoline compound by means of functionalization of organic antimony catalyzed C-H bond 湖南大学 2017-05-17 CN claimed
CN-103524465-B The synthetic method of furane derivative NANJING UNIVERSITY (CN) 2015-10-28 CN claimed
CN-104974008-A Novel method for catalytically synthesizing 1,3-diyne compound with simple, highly efficient and reusable copper catalytic system UNIV HUNAN 2015-10-14 CN claimed
CN-103408433-B Method for synthesizing propargylamine compounds UNIV HUNAN 2015-06-17 CN claimed
CN-103373892-B Three-dimensional nanometer graphene based on triptycene and preparation method thereof UNIV HUAZHONG SCIENCE TECH 2015-05-20 CN claimed
CN-102071010-B Mechanical luminescent discoloration material of 5-acetylene-2,2'-platinum dipyridyl (II) compound FUJIAN MATTER STRUCTURE 2014-03-05 CN claimed
CN-103524465-A Synthesis method of polysubstituted furan NANJING UNIVERSITY OF TECHNOLOGY 2014-01-22 CN claimed
CN-103408433-A Method for synthesizing propargylamine compounds UNIV HUNAN 2013-11-27 CN claimed
CN-103373892-A Three-dimensional nanometer graphene based on triptycene and preparation method thereof UNIV HUAZHONG SCIENCE TECH 2013-10-30 CN claimed
CN-101456801-B Method for synthesizing alpha-beta unsaturated acetyenic ketone compounds by carbonylation LANZHOU CHEM PHYS INST 2012-07-04 CN claimed
CN-101456801-A Method for synthesizing alpha-beta unsaturated acetyenic ketone compounds by carbonylation LANZHOU CHEM PHYS INST (CN) 2009-06-17 CN claimed