Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL689958 | 0.77 | KMT2A (0.51) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL688230 | 0.75 | KMT2A (0.50) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL688760 | 0.75 | KMT2A (0.50) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL7704726 | 0.75 | HDAC1 (0.53) | MEN1KMT2AKDM4ERECQLALOX5 | |
| SCHEMBL1246062 | 0.74 | MEN1 (0.67) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL4644742 | 0.74 | GAA (0.48) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL688269 | 0.73 | GAA (0.54) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL2293567 | 0.73 | MEN1 (0.60) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL4646991 | 0.73 | KMT2A (0.47) | MEN1KMT2AKDM4ERECQLLMNA | |
| SCHEMBL6809052 | 0.73 | LTB4R (0.50) | MEN1KMT2AKDM4EALOX5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1946666-A | Compounds, pharmaceutical compositions and methods for use in treating metabolic disorders | AMGEN INC (US) | 2007-04-11 | — | — | CN | disclosed |