Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 14/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.46 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30795538 | 0.87 | ALOX5 (0.49) | ALOX5EPHX2KCNT1 | |
| SCHEMBL3102218 | 0.87 | ALOX5 (0.49) | ALOX5EPHX2KCNT1 | |
| SCHEMBL30794532 | 0.87 | RAB9A (0.46) | ALOX5EPHX2KCNT1MEN1ALDH1A1 | |
| SCHEMBL30794871 | 0.86 | ALOX5 (0.53) | ALOX5EPHX2KCNT1HDAC6 | |
| SCHEMBL3099601 | 0.86 | CYP2D6 (0.47) | ALOX5EPHX2KCNT1MEN1ALDH1A1 | |
| SCHEMBL3106532 | 0.86 | ALOX5 (0.53) | ALOX5EPHX2KCNT1HDAC6 | |
| SCHEMBL30795509 | 0.86 | CYP2D6 (0.47) | ALOX5EPHX2KCNT1MEN1ALDH1A1 | |
| SCHEMBL30794759 | 0.85 | ALOX5 (0.49) | ALOX5EPHX2KCNT1MEN1ALDH1A1 | |
| SCHEMBL3106521 | 0.85 | ALOX5 (0.52) | ALOX5EPHX2KCNT1HDAC6MEN1 | |
| SCHEMBL30814227 | 0.85 | ALOX5 (0.50) | ALOX5EPHX2KCNT1HDAC6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101790374-A | Use of kncq potassium channel openers for reducing symptoms of or treating disorders or conditions wherein the dopaminergic system is disrupted | LUNDBECK & CO AS H | 2010-07-28 | — | — | CN | claimed |
| CN-101790374-A | Use of kncq potassium channel openers for reducing symptoms of or treating disorders or conditions wherein the dopaminergic system is disrupted | LUNDBECK & CO AS H | 2010-07-28 | — | — | CN | disclosed |
| CN-1777582-A | Substituted indoline and indole derivatives | LUNDBECK & CO AS H (DK) | 2006-05-24 | — | — | CN | disclosed |