Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 7/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | BAX | Q07812 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL28083694 | 0.83 | LMNA (0.48) | TDP1NR1H2ALDH1A1ACHE | |
| Phenol SCHEMBL29128638 | 0.79 | CA12 (0.48) | CA12CA1CA2GLACA3 | |
| SCHEMBL28026403 | 0.78 | TSHR (0.38) | TDP1ALDH1A1 | |
| SCHEMBL28025868 | 0.77 | TSHR (0.36) | TDP1ALDH1A1 | |
| 1-Naphthol SCHEMBL27866278 | 0.75 | CYP1A2 (0.55) | ALDH1A1KDM4E | |
| Phenol SCHEMBL28190936 | 0.69 | — | — | |
| Phenol SCHEMBL14954249 | 0.69 | — | — | |
| Phenol SCHEMBL29093222 | 0.68 | CA12 (0.65) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL3855191 | 0.67 | CA2 (0.73) | CA12CA1CA2GLACA3 | |
| Phenol SCHEMBL547014 | 0.67 | CA2 (0.73) | CA12CA1CA2GLACA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1852740-B | Prodrugs of highly branched polymers | NEKTAR THERAPEUTICS AL CORP | 2011-05-11 | — | — | CN | disclosed |
| CN-1852740-A | Prodrugs of highly branched polymers | NEKTAR THERAPEUTICS AL CORP (US) | 2006-10-25 | — | — | CN | disclosed |