Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.47 |
| ▸ | PPARG | P37231 | 5/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27630403 | 0.89 | PPARD (0.45) | PPARDPPARGPPARAPTPN1CYP1A2 | |
| SCHEMBL4853408 | 0.83 | PPARD (0.61) | PPARDPPARGPPARAPTPN1 | |
| SCHEMBL27650643 | 0.81 | PPARG (0.47) | PPARDPPARGPPARAPTPN1IKBKB | |
| SCHEMBL4852696 | 0.81 | PPARD (0.49) | PPARDPPARGPPARAPTPN1KDM4E | |
| SCHEMBL4854406 | 0.80 | PPARD (0.70) | PPARDPPARGPPARAPTPN1 | |
| SCHEMBL27630423 | 0.79 | PPARD (0.50) | PPARDPPARGPPARAPTPN1CYP1A2 | |
| SCHEMBL27664100 | 0.76 | PPARD (0.41) | PPARDPPARGPPARAKDM4EALDH1A1 | |
| SCHEMBL4467452 | 0.75 | PPARD (0.58) | PPARDPPARGPPARAPTPN1CYP1A2 | |
| SCHEMBL12151275 | 0.74 | PPARD (0.56) | PPARDPPARGPPARAPTPN1CYP1A2 | |
| SCHEMBL820999 | 0.73 | PPARD (0.56) | PPARDPPARGPPARAPTPN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809541-A | Aniline derivatives | HOFFMANN LA ROCHE (CH) | 2006-07-26 | — | — | CN | claimed |
| CN-1809541-A | Aniline derivatives | HOFFMANN LA ROCHE (CH) | 2006-07-26 | — | — | CN | disclosed |