Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 6/20 | 0.47 |
| ▸ | PPARA | Q07869 | 6/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CETP | P11597 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | UTRN | P46939 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4856754 | 0.86 | PPARD (0.45) | PPARGPPARDPPARAHDAC1HDAC6 | |
| SCHEMBL27650474 | 0.81 | PPARD (0.47) | PPARGPPARDPPARAIKBKBPTPN1 | |
| SCHEMBL27650490 | 0.80 | PPARD (0.53) | PPARGPPARDPPARA | |
| SCHEMBL27630403 | 0.73 | PPARD (0.45) | PPARGPPARDPPARAIKBKBPTPN1 | |
| SCHEMBL4853408 | 0.72 | PPARD (0.61) | PPARGPPARDPPARAPTPN1 | |
| SCHEMBL27630423 | 0.72 | PPARD (0.50) | PPARGPPARDPPARAHDAC1HDAC6 | |
| SCHEMBL4467452 | 0.71 | PPARD (0.58) | PPARGPPARDPPARAHDAC1HDAC6 | |
| SCHEMBL4854406 | 0.71 | PPARD (0.70) | PPARGPPARDPPARAPTPN1 | |
| SCHEMBL3609897 | 0.71 | PDK2 (0.39) | HDAC1HDAC6CYP2C9HDAC5 | |
| SCHEMBL4852696 | 0.70 | PPARD (0.49) | PPARGPPARDPPARAIKBKBPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1809541-A | Aniline derivatives | HOFFMANN LA ROCHE (CH) | 2006-07-26 | — | — | CN | disclosed |