Styrene

Styrene

SCHEMBL27650573

C=Cc1ccccc1.Nc1ccccc1N

nearest known ligand 0.74

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.74
TSHR P16473 4/20 0.74
ALOX15 P16050 2/20 0.53
CYP3A4 P08684 1/20 0.53
CASP1 P29466 1/20 0.53
CASP7 P55210 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MAOB P27338 3/20 0.42
HDAC8 Q9BY41 2/20 0.42
CYP19A1 P11511 2/20 0.42
MAOA P21397 2/20 0.42
MAPT P10636 2/20 0.39
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
HDAC2 Q92769 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CYP2A6 P11509 1/20 0.38
LMNA P02545 1/20 0.36
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL21485240 0.86 ALDH1A1 (0.88) ALDH1A1TSHRMAOBHDAC8CYP19A1
Styrene SCHEMBL8100955 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8
Styrene SCHEMBL140 0.86
Styrene SCHEMBL6258482 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8
Styrene SCHEMBL1226310 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8
Styrene SCHEMBL9776790 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8
Styrene SCHEMBL10892600 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8
Styrene SCHEMBL4986035 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8
Styrene SCHEMBL11144289 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8
Styrene SCHEMBL369036 0.86 ALDH1A1 (1.00) ALDH1A1TSHRSMN1; SMN2MAOBHDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100539235-C Stable organic light emitting devices using aminoanthracenes EASTMAN KODAK CO (US) 2009-09-09 CN disclosed
CN-1902768-A Stable organic light emitting devices using aminoanthracenes EASTMAN KODAK CO (US) 2007-01-24 CN disclosed