Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | ADH5 | P11766 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251863 | 0.89 | CYP1A2 (0.57) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL994454 | 0.81 | CYP1A2 (0.62) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL12017706 | 0.76 | CYP1A2 (0.62) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL18049192 | 0.73 | LOXL2 (0.55) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL16562303 | 0.72 | ALDH1A1 (0.47) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL252117 | 0.72 | CYP3A4 (0.57) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL10232920 | 0.72 | CYP1A2 (0.57) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL1237285 | 0.72 | CYP1A2 (0.57) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL12015798 | 0.72 | ALDH1A1 (0.57) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 | |
| SCHEMBL29595684 | 0.71 | CYP3A4 (1.00) | CYP1A2CYP2C19ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1902200-A | 1h-imidazoquinoline derivatives as protein kinase inhibitors | NOVARTIS AG (CH) | 2007-01-24 | — | — | CN | claimed |
| CN-1902200-A | 1h-imidazoquinoline derivatives as protein kinase inhibitors | NOVARTIS AG (CH) | 2007-01-24 | — | — | CN | disclosed |