Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | ADA | P00813 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7213383 | 0.83 | IDO1 (0.71) | SLC6A3SLC6A4SLC6A2IDO1SIGMAR1 | |
| SCHEMBL4758350 | 0.81 | IDO1 (0.73) | SLC6A3SLC6A4SLC6A2IDO1MC4R | |
| SCHEMBL21055084 | 0.81 | IDO1 (0.73) | SLC6A3SLC6A4SLC6A2IDO1MC4R | |
| SCHEMBL9791933 | 0.76 | SIGMAR1 (0.50) | SLC6A3SLC6A4SLC6A2SIGMAR1CYP1A2 | |
| SCHEMBL7250815 | 0.75 | SLC6A4 (0.71) | SLC6A3SLC6A4SLC6A2SIGMAR1CYP1A2 | |
| SCHEMBL6570349 | 0.74 | MC4R (0.49) | SLC6A3SLC6A4SLC6A2SIGMAR1MC4R | |
| SCHEMBL23013632 | 0.73 | LMNA (0.53) | SLC6A3SLC6A4SLC6A2TSHRNPC1 | |
| SCHEMBL27364544 | 0.73 | SIGMAR1 (0.50) | SLC6A3SIGMAR1MC4RCYP1A2CYP3A4 | |
| SCHEMBL23013629 | 0.73 | LMNA (0.53) | SLC6A3SLC6A4SLC6A2TSHRNPC1 | |
| SCHEMBL4935993 | 0.73 | HRH1 (0.49) | SLC6A3SLC6A4SLC6A2IDO1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1814589-A | Dermal anesthetic agents | BRIDGE PHARMA INC (US) | 2006-08-09 | — | — | CN | disclosed |