Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 9/20 | 0.43 |
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765417 | 0.89 | LMNA (0.42) | LMNATP53ALDH1A1HPGDMAPT | |
| SCHEMBL3285450 | 0.84 | F10 (0.55) | LMNATP53ALDH1A1HPGDF2 | |
| SCHEMBL5270302 | 0.78 | F10 (0.43) | LMNAF2F10ENPP2 | |
| SCHEMBL2766124 | 0.77 | LMNA (0.44) | LMNATP53MAPTKDM4E | |
| SCHEMBL2765569 | 0.76 | LMNA (0.46) | LMNATP53MAPTKDM4E | |
| SCHEMBL2767137 | 0.76 | LMNA (0.46) | LMNATP53MAPTKDM4E | |
| SCHEMBL2766277 | 0.75 | LMNA (0.43) | LMNATP53F10 | |
| SCHEMBL5269049 | 0.75 | F10 (0.42) | LMNATP53MAPTF10 | |
| SCHEMBL3285554 | 0.74 | LMNA (0.50) | LMNATP53ALDH1A1HPGDMAPT | |
| SCHEMBL2767432 | 0.73 | TP53 (0.41) | LMNATP53ALDH1A1MAPTF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858890-B1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2010-04-14 | — | — | EP | disclosed |