Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765103 | 0.89 | LMNA (0.43) | LMNAALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL2766124 | 0.87 | LMNA (0.44) | LMNAMAPTKDM4ETP53POLB | |
| SCHEMBL2765569 | 0.87 | LMNA (0.46) | LMNAMAPTKDM4ETP53POLB | |
| SCHEMBL2767137 | 0.87 | LMNA (0.46) | LMNAMAPTKDM4ETP53POLB | |
| SCHEMBL3285554 | 0.84 | LMNA (0.50) | LMNAALDH1A1HPGDRXFP1MAPT | |
| SCHEMBL5266162 | 0.84 | F10 (0.42) | LMNAMAPTKDM4ETP53POLB | |
| SCHEMBL5264221 | 0.82 | TP53 (0.41) | LMNAALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL2766741 | 0.81 | POLB (0.41) | LMNAALDH1A1MAPTKDM4ETP53 | |
| SCHEMBL2766936 | 0.81 | LMNA (0.40) | LMNAMAPTKDM4ETP53POLB | |
| SCHEMBL2765159 | 0.81 | POLB (0.41) | LMNAALDH1A1MAPTKDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858890-B1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2010-04-14 | — | — | EP | disclosed |