Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 20/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 12/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 2/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29394472 | 1.00 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL14472809 | 0.92 | CCR5 (0.85) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL13864750 | 0.89 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL13326646 | 0.89 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL27651253 | 0.88 | CCR5 (0.79) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL4979182 | 0.85 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL4453513 | 0.85 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL4979191 | 0.85 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL28781069 | 0.85 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 | |
| SCHEMBL5076337 | 0.83 | CCR5 (1.00) | CCR5CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1789263-A | Substituted piperazidine-piperidine amide compound, preparation method and uses thereof | SHANGHAI INST MATERIA MEDICA (CN) | 2006-06-21 | — | — | CN | disclosed |