Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL27853012 | 0.85 | TDP1 (0.35) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27853000 | 0.84 | POLB (0.40) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27965686 | 0.82 | SSTR4 (0.33) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27651272 | 0.81 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27847387 | 0.81 | TDP1 (0.43) | TDP1BRD4CREBBP | |
| Tert-Butyl Formate SCHEMBL28312695 | 0.81 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27847386 | 0.81 | TDP1 (0.43) | TDP1BRD4CREBBP | |
| Tert-Butyl Formate SCHEMBL28052001 | 0.81 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL28758511 | 0.75 | TDP1 (0.43) | TDP1 | |
| Tert-Butyl Formate SCHEMBL27886925 | 0.75 | TDP1 (0.43) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490035-B | Amino-piperidine derivatives as CETP inhibitors | NOVARTIS AG | 2013-02-13 | — | — | CN | disclosed |
| CN-101490035-A | Amino-piperidine derivatives as CETP inhibitors | NOVARTIS AG (CH) | 2009-07-22 | — | — | CN | disclosed |