Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27953752 | 0.84 | LMNA (0.39) | HCAR2HSP90AA1LMNAMAPTALDH1A1 | |
| SCHEMBL23777655 | 0.80 | NOTUM (0.54) | HCAR2LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL27610637 | 0.79 | AKR1C3 (0.49) | HSP90AA1LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4081817 | 0.79 | HCAR2 (0.56) | HCAR2LMNAMAPTALDH1A1CYP3A4 | |
| SCHEMBL17422311 | 0.79 | KDM4E (0.37) | LMNAALDH1A1SMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL3187419 | 0.77 | MEN1 (0.48) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13416764 | 0.76 | CCR4 (0.43) | HSP90AA1MAPTCYP3A4HPGDCRHBP | |
| SCHEMBL3194905 | 0.73 | HTT (0.36) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL5414205 | 0.72 | CHRM2 (0.52) | LMNAALDH1A1SMN1; SMN2HPGDNOTUM | |
| SCHEMBL631834 | 0.70 | MAPT (0.68) | LMNAMAPTALDH1A1GFERSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1780818-A | Phenyl-substituted cyclic derivatives | FMC CORP (US) | 2006-05-31 | — | — | CN | disclosed |