Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 4/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 4/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 4/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 7/20 | 0.31 |
| ▸ | CA2 | P00918 | 7/20 | 0.31 |
| ▸ | CA9 | Q16790 | 7/20 | 0.31 |
| ▸ | CA12 | O43570 | 2/20 | 0.30 |
| ▸ | CA3 | P07451 | 2/20 | 0.30 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
| ▸ | CA6 | P23280 | 2/20 | 0.30 |
| ▸ | CA5A | P35218 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6849661 | 0.76 | KMT2A (0.39) | MEN1ALDH1A1LMNAKMT2AL3MBTL1 | |
| SCHEMBL16382363 | 0.69 | CA12 (0.30) | CA2CA9CA12CA7CA14 | |
| SCHEMBL27631550 | 0.69 | CA1 (0.32) | CA1CA2CA9 | |
| SCHEMBL6764098 | 0.67 | NPSR1 (0.40) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL25235972 | 0.67 | EPHX1 (0.36) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL27396997 | 0.66 | CA1 (0.42) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL8506764 | 0.65 | CA1 (0.46) | ALDH1A1LMNACA1CA2CA9 | |
| SCHEMBL5984526 | 0.65 | — | — | |
| SCHEMBL1279310 | 0.65 | — | — | |
| SCHEMBL27706075 | 0.64 | CA1 (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1839118-B | Methods and compositions for treating amyloid-related diseases | BELLUS HEALTH INTERNATIONAL LTD | 2010-06-16 | — | — | CN | disclosed |
| CN-101712640-A | methods and compositions for treating amyloid-related diseases | BELLUS HEALTH INTERNAT LT | 2010-05-26 | — | — | CN | disclosed |
| CN-1839118-A | Methods and compositions for treating amyloid-related diseases | NEUROCHEM INTERNAT LTD (CH) | 2006-09-27 | — | — | CN | disclosed |