Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | FABP6 | P51161 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177032 | 0.79 | KMT2A (0.39) | SLC6A3ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL20416995 | 0.78 | KDM4E (0.36) | SLC6A3ALDH1A1KDM4E | |
| SCHEMBL27612020 | 0.78 | GABRA5 (0.44) | ALDH1A1SMN1; SMN2NPC1RAB9AMAPT | |
| SCHEMBL13624605 | 0.77 | SLC6A3 (0.40) | SLC6A3ALDH1A1KDM4E | |
| SCHEMBL15177030 | 0.77 | MAPT (0.40) | SLC6A3ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15177027 | 0.77 | SLC6A3 (0.36) | SLC6A3ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL1399852 | 0.76 | — | — | |
| SCHEMBL15177026 | 0.73 | SMN1; SMN2 (0.34) | SLC6A3ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL15177021 | 0.73 | HDAC1 (0.35) | SLC6A3ALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL16095853 | 0.73 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102329267-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-25 | — | — | CN | disclosed |
| CN-102311387-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-11 | — | — | CN | disclosed |
| CN-1934088-A | As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |