Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15271041 | 0.81 | EHMT2 (0.50) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL15271518 | 0.78 | EHMT2 (0.50) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL15271760 | 0.76 | EHMT2 (0.48) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL12949631 | 0.76 | EHMT2 (0.48) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL28455598 | 0.76 | EHMT2 (0.48) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL10640635 | 0.74 | EHMT2 (0.54) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL2847414 | 0.73 | ALDH1A1 (0.41) | CRBNDDB1ALDH1A1KMT2APOLB | |
| SCHEMBL2847417 | 0.73 | ALDH1A1 (0.41) | CRBNDDB1ALDH1A1KMT2APOLB | |
| SCHEMBL16225064 | 0.72 | OPRM1 (0.37) | ALDH1A1KMT2AHTR2CGRM5NPC1 | |
| SCHEMBL4675115 | 0.70 | KMT2A (0.57) | CRBNDDB1EHMT2EHMT1APOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102329267-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-25 | — | — | CN | disclosed |
| CN-102311387-A | 6-substituted 2,3,4, 5-tetrahydro-1H-benzo [d] aza as 5-HT2Creceptor agonists | LILLY CO ELI | 2012-01-11 | — | — | CN | disclosed |
| CN-1934088-A | As 5-HT2c6-substituted 2,3,4, 5-tetrahydro-1H-benzo [ d ] receptor agonists]Aza * | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |