Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19751374 | 0.82 | TAAR1 (0.44) | TAAR1IDO1ESR1ESR2MAOB | |
| SCHEMBL9200966 | 0.79 | TAAR1 (0.60) | TAAR1IDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL1631126 | 0.78 | MAOB (0.54) | TAAR1IDO1AGXTALDH1A1MAPK1 | |
| SCHEMBL24423317 | 0.77 | ESR1 (0.48) | ESR1ESR2ALDH1A1 | |
| SCHEMBL9351968 | 0.75 | TAAR1 (0.52) | TAAR1IDO1AGXTPARP1MAOB | |
| SCHEMBL1539285 | 0.74 | TAAR1 (0.52) | TAAR1IDO1AGXTMAOBPYCR1 | |
| SCHEMBL4717 | 0.73 | CALM1 (0.57) | TAAR1IDO1AGXTALDH1A1MAOB | |
| SCHEMBL31499406 | 0.73 | CALM1 (0.57) | TAAR1IDO1AGXTALDH1A1MAOB | |
| SCHEMBL4065253 | 0.72 | — | — | |
| SCHEMBL29279068 | 0.71 | TAAR1 (0.44) | TAAR1IDO1AGXTMAOBPYCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1802366-B | C-glycoside derivatives and salts thereof | ASTELLAS PHARMA INC | 2010-12-22 | — | — | CN | disclosed |
| CN-1802366-A | C-glycoside derivatives and salts thereof | ASTELLAS PHARMA INC (JP) | 2006-07-12 | — | — | CN | disclosed |