Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 5/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10463554 | 0.89 | TBXAS1 (0.57) | HTR1ADRD2HTR2APDE3BPDE3A | |
| SCHEMBL27889759 | 0.87 | CYP17A1 (0.54) | PDE3BPDE3ATBXAS1CYP19A1CYP11B1 | |
| SCHEMBL10461476 | 0.82 | TBXAS1 (0.55) | HTR1ADRD2HTR2APDE3BPDE3A | |
| Hydrochloric Acid SCHEMBL10464252 | 0.81 | TBXAS1 (0.54) | HTR1ADRD2HTR2APDE3BPDE3A | |
| SCHEMBL10464344 | 0.81 | HTR1A (0.57) | HTR1ADRD2HTR2APDE3BPDE3A | |
| SCHEMBL8670836 | 0.78 | AHR (0.59) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| Acetic Acid SCHEMBL10463268 | 0.77 | TBXAS1 (0.52) | HTR1ADRD2HTR2APDE3BPDE3A | |
| SCHEMBL14560260 | 0.75 | HTR1A (0.64) | HTR1ADRD2HTR2AADRA1DADRA1A | |
| SCHEMBL4816440 | 0.74 | TBXAS1 (0.48) | TBXAS1CYP19A1KMT2ACYP1A2CYP17A1 | |
| SCHEMBL14560259 | 0.74 | HTR1A (0.63) | HTR1ADRD2HTR2AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1906160-A | Imidazole derivatives, processes for preparing them and their uses | UCB SA (BE) | 2007-01-31 | — | — | CN | claimed |
| CN-1906160-A | Imidazole derivatives, processes for preparing them and their uses | UCB SA (BE) | 2007-01-31 | — | — | CN | disclosed |