Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765292 | 0.84 | ECE1 (0.46) | HPGDTSHRRAB9AMAPTALDH1A1 | |
| SCHEMBL2764014 | 0.78 | HPGD (0.63) | HPGDTSHRNPSR1LMNAHSD17B10 | |
| SCHEMBL28268426 | 0.77 | CYP1A2 (0.59) | HPGDTSHRNPSR1LMNAHSD17B10 | |
| SCHEMBL4639967 | 0.76 | RAB9A (0.54) | HPGDTSHRNPSR1RAB9AMAPT | |
| SCHEMBL2764450 | 0.76 | HPGD (1.00) | HPGDTSHRNPSR1LMNAHSD17B10 | |
| SCHEMBL2764743 | 0.75 | HDAC1 (0.40) | HPGDTSHRLMNAHSD17B10RAB9A | |
| SCHEMBL19609101 | 0.75 | RAB9A (0.55) | HPGDTSHRNPSR1LMNARAB9A | |
| SCHEMBL1549088 | 0.75 | RAB9A (0.55) | HPGDTSHRNPSR1RAB9AMAPT | |
| SCHEMBL18296687 | 0.73 | RAB9A (0.50) | HPGDTSHRNPSR1LMNAHSD17B10 | |
| SCHEMBL1548729 | 0.73 | RAB9A (0.59) | HPGDTSHRNPSR1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| CN-100491355-C | Cyclic diamine compound having five-membered cyclic group | KOWA CO (JP) | 2009-05-27 | — | — | CN | disclosed |
| CN-1522250-A | Cyclic diamine compound having five-membered cyclic group | ������������ʽ���� | 2004-08-18 | — | — | CN | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |