Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.34 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27654170 | 0.88 | AR (0.52) | ARKIF11SRD5A1MTNR1A | |
| SCHEMBL30738393 | 0.88 | AR (0.52) | ARKIF11SRD5A1MTNR1A | |
| SCHEMBL6754129 | 0.81 | AR (0.46) | ARKIF11SRD5A1MTNR1ACYP26A1 | |
| SCHEMBL6754125 | 0.81 | AR (0.46) | ARKIF11SRD5A1MTNR1ACYP26A1 | |
| SCHEMBL6754126 | 0.81 | AR (0.46) | ARKIF11SRD5A1MTNR1ACYP26A1 | |
| SCHEMBL9064740 | 0.79 | AR (0.50) | ARMTNR1A | |
| Ethoxycarbonyl Group SCHEMBL27550175 | 0.78 | AR (0.36) | ARKIF11 | |
| Ethoxycarbonyl Group SCHEMBL27493742 | 0.78 | AR (0.36) | ARKIF11 | |
| SCHEMBL27574277 | 0.77 | AR (0.40) | ARFFAR1KIF11SRD5A1 | |
| SCHEMBL22297852 | 0.76 | AR (0.44) | ARKIF11MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843887-A | Naphthyridinone derivatives and its purposes in treatment arrhythmia cordis | 诺华股份有限公司 | 2019-06-04 | — | — | CN | disclosed |