Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 5/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22297828 | 0.88 | AR (0.43) | ARMTNR1AESR1ESR2ADRA2A | |
| SCHEMBL14822782 | 0.87 | MTNR1A (0.36) | ARMTNR1AKIF11ESR1ESR2 | |
| SCHEMBL27654170 | 0.87 | AR (0.52) | ARMTNR1AKIF11PNMT | |
| SCHEMBL30738393 | 0.87 | AR (0.52) | ARMTNR1AKIF11PNMT | |
| SCHEMBL13986217 | 0.80 | AR (0.41) | ARKIF11ESR1ESR2HRH3 | |
| SCHEMBL13920389 | 0.78 | KIF11 (0.37) | KIF11ESR1ESR2TRPV1TRPV4 | |
| SCHEMBL22298131 | 0.78 | AR (0.43) | ARMTNR1AKIF11ESR1ESR2 | |
| SCHEMBL14767430 | 0.78 | AR (0.43) | ARMTNR1AKIF11ESR1ESR2 | |
| SCHEMBL10841342 | 0.78 | AR (0.43) | ARMTNR1AESR1ESR2ADRA2A | |
| SCHEMBL6754129 | 0.77 | AR (0.46) | ARMTNR1AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689860-A1 | SULFONYL-SUBSTITUTED BICYCLIC COMPOUND WHICH ACTS AS ROR INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2020-08-05 | — | — | EP | disclosed |