Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692400 | 0.81 | MAPT (0.66) | FAAHMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL3664984 | 0.79 | SMN1; SMN2 (0.68) | HSD17B10FAAHSMN1; SMN2MAPTPOLB | |
| SCHEMBL4692437 | 0.77 | FAAH (0.58) | HSD17B10TSHRFAAHSMN1; SMN2MAPT | |
| SCHEMBL25326552 | 0.77 | SYK (0.63) | — | |
| SCHEMBL2763992 | 0.77 | TDP1 (0.50) | HSD17B10TSHRFAAHMEN1KMT2A | |
| SCHEMBL4689595 | 0.76 | MAPT (0.58) | FAAHMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL5340156 | 0.76 | FAAH (0.57) | HSD17B10FAAHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5022767 | 0.76 | TSHR (0.58) | TSHRFAAHMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4222851 | 0.75 | SMN1; SMN2 (0.50) | FAAHMEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL2562448 | 0.74 | FAAH (0.53) | TSHRFAAHSMN1; SMN2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |