Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACVR1 | Q04771 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2765410 | 0.81 | ACVR1 (0.46) | ACVR1 | |
| SCHEMBL2763861 | 0.81 | ACVR1 (0.46) | ACVR1CYP3A4 | |
| SCHEMBL2764801 | 0.75 | ACVR1 (0.41) | ACVR1CYP3A4 | |
| SCHEMBL20588524 | 0.73 | ACVR1 (0.49) | ACVR1 | |
| Hydrochloric Acid SCHEMBL20589683 | 0.72 | ACVR1 (0.48) | ACVR1 | |
| SCHEMBL5683622 | 0.69 | TGFBR1 (0.45) | ACVR1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5679898 | 0.69 | ALDH1A1 (0.43) | ACVR1KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL11179651 | 0.69 | USP2 (0.69) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL10334149 | 0.69 | KDM4E (0.75) | KDM4EMEN1KMT2AALDH1A1TDP1 | |
| Hydrochloric Acid SCHEMBL11185330 | 0.68 | USP2 (0.67) | KDM4EMEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1400515-B1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | KOWA CO (JP) | 2010-04-14 | — | — | EP | disclosed |
| EP-1400515-A1 | CYCLIC DIAMINE COMPOUND HAVING FIVE-MEMBERED CYCLIC GROUP | Kowa Co., Ltd. (JP) | 2004-03-24 | — | — | EP | disclosed |
| US-6472386-B1 | Cyclic diamine compound with 5-membered ring groups | KOWA CO., LTD. (JP) | 2002-10-29 | — | — | US | disclosed |