Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PRKCA | P17252 | 1/20 | 0.48 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789673 | 0.85 | ALOX5 (0.56) | ALOX5TAAR1THRBPRKCAPRKCD | |
| SCHEMBL23049789 | 0.85 | PRKCA (0.60) | THRBPRKCAPRKCDMAOBACP3 | |
| SCHEMBL28561124 | 0.82 | TAAR1 (0.57) | ALOX5TAAR1PRKCAPRKCDMAOB | |
| SCHEMBL22857498 | 0.82 | PPARA (0.47) | ALOX5TAAR1MAOBHDAC1HDAC8 | |
| SCHEMBL3248128 | 0.81 | ALOX5 (0.50) | ALOX5TAAR1THRBPRKCAPRKCD | |
| SCHEMBL2761647 | 0.81 | ALOX5 (0.52) | ALOX5TAAR1THRBPRKCAPRKCD | |
| SCHEMBL901880 | 0.80 | FFAR4 (0.55) | ALOX5TAAR1THRBPRKCAPRKCD | |
| SCHEMBL15736550 | 0.80 | TAAR1 (0.47) | TAAR1THRBPRKCAPRKCDMAOB | |
| Hydrochloric Acid SCHEMBL27533447 | 0.79 | ALOX5 (0.50) | ALOX5TAAR1MAOBSIRT2KDM4E | |
| SCHEMBL27986144 | 0.79 | FFAR1 (0.46) | MAOBFFAR4KDM4EHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105209446-A | GPR120 agonists for the treatment of type ii diabetes | JANSSEN PHARMACEUTICA NV | 2015-12-30 | — | — | CN | disclosed |
| CN-1922143-A | Alpha- (trifluoromethyl-substituted aryloxy, arylamino, arylthio or arylmethyl) -trifluoromethyl-substituted phenylacetic acids and derivatives as antidiabetics | METABOLEX INC (US) | 2007-02-28 | — | — | CN | disclosed |