Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.53 |
| ▸ | RELA | Q04206 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27641903 | 0.86 | RAB9A (0.61) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL28135259 | 0.85 | NPC1 (0.63) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL28135372 | 0.84 | BIRC5 (0.50) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL9697154 | 0.83 | CLK4 (0.53) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL29637608 | 0.83 | CLK4 (0.57) | NPC1RAB9ACLK4DYRK1AADRB2 | |
| SCHEMBL1000179 | 0.83 | NPC1 (0.59) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL12619988 | 0.82 | ALDH1A1 (0.68) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL14961829 | 0.82 | CLK4 (0.61) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL3946608 | 0.82 | ALDH1A1 (0.68) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL25224950 | 0.81 | CLK4 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1902295-A | Phosphorescent polymeric organic semiconductor emitter materials based on perarylated boranes, method for the production thereof and use thereof | OSRAM OPTO SEMICONDUCTORS GMBH (DE) | 2007-01-24 | — | — | CN | disclosed |