Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045736 | 0.87 | NPC1 (0.49) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL3661643 | 0.85 | HPGD (0.54) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| Hydrochloric Acid SCHEMBL27759786 | 0.84 | HPGD (0.52) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL4746226 | 0.83 | SMN1; SMN2 (0.50) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL27903906 | 0.83 | HTT (0.56) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL27543099 | 0.82 | HTT (0.51) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL5242291 | 0.81 | PARP1 (0.51) | HPGDALDH1A1KDM4EHSD17B10NPC1 | |
| SCHEMBL29738645 | 0.80 | NPC1 (0.64) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL878658 | 0.80 | NPC1 (0.64) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL4765102 | 0.80 | HMGCR (0.53) | HPGDALDH1A1KDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1829709-A | Bicyclic imidazol derivatives against flaviviridae | GENELABS TECH INC (US) | 2006-09-06 | — | — | CN | disclosed |