Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29466500 | 0.89 | HDAC4 (0.59) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL27903906 | 0.87 | HTT (0.56) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL1957953 | 0.86 | SMN1; SMN2 (0.56) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| Benzylacetone SCHEMBL27465961 | 0.85 | ALDH1A1 (0.51) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL5242291 | 0.85 | PARP1 (0.51) | NPC1RAB9AALDH1A1HPGDKDM4E | |
| SCHEMBL29931828 | 0.84 | NPC1 (0.58) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL341046 | 0.84 | NPC1 (0.58) | SMN1; SMN2LMNANPC1RAB9ATP53 | |
| SCHEMBL27655331 | 0.83 | HPGD (0.47) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL978349 | 0.83 | NPC1 (0.49) | SMN1; SMN2NPC1RAB9ATP53ALDH1A1 | |
| SCHEMBL27532250 | 0.83 | MAPT (0.51) | SMN1; SMN2LMNANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106519630-A | Antifogging polycarbonate material and preparation method thereof | 南京悠谷知识产权服务有限公司 | 2017-03-22 | — | — | CN | disclosed |
| WO-2008123821-A1 | 4, 5-DIHYDRO-LH-IMIDAZOL-2-AMINE DERIVATIVES FOR USE IN THE TREATMENT OF RESPIRATORY, CARDIOVASCULAR, NEUROLOGICAL OR GASTROINTESTINAL DISORDERS | ALBIREO AB (SE) | 2008-10-16 | — | — | WO | disclosed |
| CN-1098279-C | Polymerized microemulsion pressure-sensitive adhesive compositions and method of preparing and using same | MINNESOTA MINING & MFG (US) | 2003-01-08 | — | — | CN | disclosed |
| CN-1191546-A | Polymerized microemulsion pressure sensitive adhesive compositions and methods of making and using the same | MINNESOTA MINING & MFG (US) | 1998-08-26 | — | — | CN | disclosed |
| US-4745505-A | Magnetic head with a modified gap filler | U.S. PHILIPS CORPORATION (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0130652-A1 | Magnetic head and method of manufacturing same | Koninklijke Philips Electronics N.V. (NL) | 1985-01-09 | — | — | EP | disclosed |