Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5045736 | 0.85 | NPC1 (0.49) | HMGCRSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL27455646 | 0.82 | HMGCR (0.50) | HMGCRSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL28323667 | 0.81 | LMNA (0.49) | RAB9AHPGDTNFSF11MAPTALDH1A1 | |
| SCHEMBL27655331 | 0.80 | HPGD (0.47) | HMGCRSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL27977856 | 0.78 | MAPT (0.55) | SMN1; SMN2NPC1RAB9AHPGDTNFSF11 | |
| SCHEMBL878658 | 0.78 | NPC1 (0.64) | HMGCRSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29738645 | 0.78 | NPC1 (0.64) | HMGCRSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL4764754 | 0.76 | HMGCR (0.72) | HMGCRMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17746918 | 0.75 | HMGCR (0.78) | HMGCRSMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL28738497 | 0.74 | MYC (0.52) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008208134-A | PROCESS FOR PREPARATION OF PHARMACOLOGICALLY ACTIVE alpha-ASARONE DERIVED FROM TOXIC beta-ASARONE-RICH CALAMUS OIL | COUNCIL SCIENT IND RES | 2008-09-11 | — | — | JP | disclosed |