Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253413 | 0.91 | TDP1 (0.53) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL4547929 | 0.82 | SMN1; SMN2 (0.58) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL27655362 | 0.78 | SMN1; SMN2 (0.50) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL8031114 | 0.75 | RAB9A (0.61) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL2938583 | 0.73 | MEN1 (0.69) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL23399794 | 0.72 | LMNA (0.52) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL14113376 | 0.72 | LMNA (0.56) | TDP1KDM4EMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL4130422 | 0.72 | RAB9A (0.66) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL20037317 | 0.72 | LMNA (0.63) | TDP1KDM4EPOLBAPEX1RAB9A | |
| SCHEMBL2937866 | 0.71 | RAB9A (0.64) | TDP1KDM4EPOLBAPEX1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1829709-A | Bicyclic imidazol derivatives against flaviviridae | GENELABS TECH INC (US) | 2006-09-06 | — | — | CN | disclosed |