Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.44 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28030353 | 0.86 | LMNA (0.45) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 | |
| SCHEMBL17591689 | 0.82 | LMNA (0.54) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 | |
| SCHEMBL27956700 | 0.78 | L3MBTL1 (0.49) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 | |
| SCHEMBL15591082 | 0.78 | LMNA (0.46) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 | |
| SCHEMBL7995329 | 0.76 | LMNA (0.45) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 | |
| SCHEMBL7378506 | 0.76 | LMNA (0.45) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 | |
| SCHEMBL2370434 | 0.76 | L3MBTL1 (0.51) | LMNASMN1; SMN2TBXAS1F7F3 | |
| SCHEMBL12883291 | 0.76 | L3MBTL1 (0.51) | LMNASMN1; SMN2TBXAS1F7F3 | |
| SCHEMBL4775271 | 0.74 | SMN1; SMN2 (0.49) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 | |
| SCHEMBL4779810 | 0.74 | SMN1; SMN2 (0.49) | LMNAGRM8GRM4SMN1; SMN2TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1761673-A | guanidine derivatives and their use as neuropeptide FF receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2006-04-19 | — | — | CN | claimed |
| CN-100355758-C | Guanidine derivatives and use thereof as neuropeptide FF receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2007-12-19 | — | — | CN | disclosed |
| CN-1761673-A | guanidine derivatives and their use as neuropeptide FF receptor antagonists | ACTELION PHARMACEUTICALS LTD (CH) | 2006-04-19 | — | — | CN | disclosed |