Fluoride

Fluoride

SCHEMBL27656103

F.c1ccc(-c2ccccc2-c2ccccc2)cc1

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.58
HSD17B10 Q99714 2/20 0.58
HPGD P15428 1/20 0.58
BCL2L1 Q07817 1/20 0.58
CYP2A6 P11509 1/20 0.58
MAPK1 P28482 1/20 0.58
BACE1 P56817 1/20 0.53
DPP4 P27487 1/20 0.50
PTGS2 P35354 1/20 0.50
HDAC4 P56524 1/20 0.48
HDAC2 Q92769 1/20 0.48
HDAC8 Q9BY41 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
GPR55 Q9Y2T6 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
BCAT2 O15382 1/20 0.46
NISCH Q9Y2I1 1/20 0.44
DCUN1D1 Q96GG9 1/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28035419 0.96 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL2361430 0.96 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL21447 0.96 ALDH1A1 (0.61) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Ammonia Solution, Strong SCHEMBL4839393 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Ammonia Solution, Strong SCHEMBL7129970 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Biphenyl SCHEMBL1994657 0.92 ALDH1A1 (0.69) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL10908520 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
Water SCHEMBL9138909 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL13387362 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL9419397 0.92 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113527318-B Preparation of carbon-carbon double-bond-connected covalent organic microporous material and application of material in photolysis of water 山东师范大学 2022-06-21 CN claimed
CN-118307575-B Synthesis method of 4' -alkyl-3-fluoro-4-biphenylboronic acid 山东盛华电子新材料有限公司 2024-08-02 CN disclosed
CN-118307575-A Synthesis method of 4' -alkyl-3-fluoro-4-biphenylboronic acid 山东盛华电子新材料有限公司 2024-07-09 CN disclosed
CN-1928668-B alignment method of negative dielectric anisotropic liquid crystal TOPPOLY OPTOELECTRONICS CORP 2010-05-12 CN disclosed
CN-1928668-A Alignment method of negative dielectric anisotropic liquid crystal TOPPOLY OPTOELECTRONICS CORP (CN) 2007-03-14 CN disclosed