SCHEMBL27657488

SCHEMBL27657488

Oc1ccc(O)c(Cc2ccccc2)c1Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDH1 O75874 1/20 0.58
BCL2 P10415 1/20 0.56
BCL2L1 Q07817 1/20 0.56
CALM1 P0DP23 1/20 0.55
HSD17B10 Q99714 2/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
ALOX15 P16050 2/20 0.50
CYP3A4 P08684 1/20 0.50
HPGD P15428 1/20 0.50
HIF1A Q16665 1/20 0.50
HNF4A P41235 1/20 0.48
ALOX5 P09917 1/20 0.48
CYP1A2 P05177 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
HTT P42858 2/20 0.45
SHBG P04278 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1841243 0.89 BCL2 (0.57) IDH1BCL2BCL2L1CALM1HSD17B10
SCHEMBL29713477 0.89 BCL2 (0.57) IDH1BCL2BCL2L1CALM1HSD17B10
SCHEMBL875676 0.87 BCL2 (0.54) IDH1BCL2BCL2L1CALM1HSD17B10
SCHEMBL9790331 0.87 MEN1 (0.50) IDH1BCL2BCL2L1CALM1HSD17B10
SCHEMBL2353814 0.87 IDH1 (0.49) IDH1BCL2BCL2L1CALM1HSD17B10
SCHEMBL9244765 0.84 HNF4A (0.59) IDH1BCL2BCL2L1MEN1KMT2A
SCHEMBL1644555 0.83 BCL2 (0.55) IDH1BCL2BCL2L1HSD17B10MEN1
SCHEMBL27885818 0.82 HTT (0.47) IDH1BCL2BCL2L1MEN1KMT2A
SCHEMBL7582785 0.81 MEN1 (0.49) IDH1BCL2BCL2L1CALM1HSD17B10
SCHEMBL3634979 0.81 SHBG (0.48) IDH1BCL2BCL2L1CALM1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1793100-A Process for synthesizing cozymase Q10 UNIV ZHEJIANG TECHNOLOGY (CN) 2006-06-28 CN disclosed