Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089033 | 0.94 | LMNA (0.46) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL28089031 | 0.94 | LMNA (0.46) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL7912193 | 0.86 | LMNA (0.56) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL4781590 | 0.82 | LMNA (0.73) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL23710839 | 0.82 | LMNA (0.41) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL4776978 | 0.80 | LMNA (0.50) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL1219703 | 0.79 | LMNA (0.54) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL4730828 | 0.79 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL23844645 | 0.79 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL8367371 | 0.79 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101346373-B | 2,2',6,6' -tetraoxazoline biphenyl ligand and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2012-01-18 | — | — | CN | disclosed |
| CN-100349880-C | 2,2', 6,6'-tetraoxazoline diphenyl ligancy and preparation process thereof | UNIV SHANGHAI JIAOTONG (CN) | 2007-11-21 | — | — | CN | disclosed |
| CN-1793130-A | 2,2', 6,6'-tetraoxazoline diphenyl ligancy and preparation process thereof | UNIV SHANGHAI JIAOTONG (CN) | 2006-06-28 | — | — | CN | disclosed |