Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 2/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28089033 | 1.00 | LMNA (0.46) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL27657494 | 0.94 | LMNA (0.48) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL1219703 | 0.87 | LMNA (0.54) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL1222862 | 0.85 | LMNA (0.52) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL1223599 | 0.85 | LMNA (0.52) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| Methyl Alcohol SCHEMBL28137239 | 0.85 | LMNA (0.52) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL2346969 | 0.85 | LMNA (0.52) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL1222755 | 0.85 | LMNA (0.52) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL8975153 | 0.83 | LMNA (0.70) | LMNAKDM4ECNR1ADRA1ATDP1 | |
| SCHEMBL16628357 | 0.81 | LMNA (0.67) | LMNAKDM4ECNR1ADRA1ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349156-A | Pyridine-2-amides capable of being used as CB2 agonist | 霍夫曼-拉罗奇有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-103608332-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2016-09-28 | — | — | CN | claimed |