Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | AKT2 | P31751 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28440401 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL28449861 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL28141364 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL27973060 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL29161797 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL28054051 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL28148974 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| SCHEMBL27918142 | 0.98 | TBXAS1 (0.44) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| SCHEMBL15657207 | 0.98 | TBXAS1 (0.44) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| SCHEMBL27908258 | 0.98 | TBXAS1 (0.44) | TBXAS1CYP17A1PIK3R1AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1922152-A | Novel imidazolium compound | KANTO KAGAKU (JP) | 2007-02-28 | — | — | CN | disclosed |