Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 8/20 | 0.40 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | AKT2 | P31751 | 2/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.33 |
| ▸ | AKT3 | Q9Y243 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28449861 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL27657523 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL28141364 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL27973060 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL29161797 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL28054051 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| Bromide SCHEMBL28148974 | 1.00 | TBXAS1 (0.42) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| SCHEMBL27918142 | 0.98 | TBXAS1 (0.44) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| SCHEMBL15657207 | 0.98 | TBXAS1 (0.44) | TBXAS1CYP17A1PIK3R1AKT1AKT2 | |
| SCHEMBL27908258 | 0.98 | TBXAS1 (0.44) | TBXAS1CYP17A1PIK3R1AKT1AKT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118272010-A | Aqueous iodine-fixing binder and preparation method and application thereof | 广东工业大学 | 2024-07-02 | — | — | CN | claimed |
| CN-116705518-A | Ionic liquid crystal electrolyte, gel electrode and flexible supercapacitor prepared from ionic liquid crystal electrolyte | 烟台大学 | 2023-09-05 | — | — | CN | claimed |
| CN-118272010-B | Aqueous iodine-fixing binder and preparation method and application thereof | 广东工业大学 | 2024-07-26 | — | — | CN | disclosed |
| CN-118272010-A | Aqueous iodine-fixing binder and preparation method and application thereof | 广东工业大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-114887112-B | Preparation method and application of imidazolium ionic liquid/polyvinyl alcohol pressure sensing antibacterial hydrogel dressing | 大连工业大学 | 2023-09-22 | — | — | CN | disclosed |
| CN-116705518-A | Ionic liquid crystal electrolyte, gel electrode and flexible supercapacitor prepared from ionic liquid crystal electrolyte | 烟台大学 | 2023-09-05 | — | — | CN | disclosed |
| CN-114600894-B | Corrosion inhibition bactericide for oil field and preparation method thereof | 河南省科学院同位素研究所有限责任公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-114600894-A | Corrosion inhibition bactericide for oil field and preparation method thereof | 河南省科学院同位素研究所有限责任公司 | 2022-06-10 | — | — | CN | disclosed |
| CN-111592612-B | Polyion liquid inhibitor and preparation method and application thereof | 中国科学院过程工程研究所 | 2021-07-20 | — | — | CN | disclosed |
| CN-111592612-A | Polyion liquid inhibitor and preparation method and application thereof | 中国科学院过程工程研究所 | 2020-08-28 | — | — | CN | disclosed |