Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 2/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429673 | 0.79 | GUSB (0.31) | — | |
| SCHEMBL237122 | 0.79 | ALDH1A1 (0.53) | ALDH1A1RXFP1NUDT1KMT2A | |
| SCHEMBL31561546 | 0.79 | ALDH1A1 (0.53) | ALDH1A1RXFP1NUDT1KMT2A | |
| SCHEMBL2125263 | 0.79 | GUSB (0.31) | — | |
| SCHEMBL2822837 | 0.76 | — | — | |
| SCHEMBL2934833 | 0.76 | ALDH1A1 (0.50) | ALDH1A1RXFP1ADORA1ADORA2ACLK1 | |
| SCHEMBL3963577 | 0.76 | ALDH1A1 (0.50) | ALDH1A1RXFP1FGFR1SRCDHFR | |
| SCHEMBL5034214 | 0.76 | ALDH1A1 (0.50) | ALDH1A1RXFP1CLK1CDK5CDK5R1 | |
| SCHEMBL8447336 | 0.76 | ALDH1A1 (0.50) | ALDH1A1RXFP1FGFR1NUDT1GFER | |
| SCHEMBL28016408 | 0.76 | ALDH1A1 (0.50) | ALDH1A1RXFP1CLK1CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1860227-B | method for sequence saturation mutagenesis (SeSaM) | BASF AG | 2012-05-16 | — | — | CN | claimed |
| CN-1860227-A | A process for sequence saturation mutagenesis (SeSaM) | BASF AG (DE) | 2006-11-08 | — | — | CN | claimed |
| CN-1860227-B | method for sequence saturation mutagenesis (SeSaM) | BASF AG | 2012-05-16 | — | — | CN | disclosed |
| CN-1860227-A | A process for sequence saturation mutagenesis (SeSaM) | BASF AG (DE) | 2006-11-08 | — | — | CN | disclosed |