SCHEMBL8447336

SCHEMBL8447336

Cc1nc2nc(N)ncc2[nH]1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.46
RXFP1 Q9HBX9 2/20 0.44
NUDT1 P36639 4/20 0.41
FGFR1 P11362 1/20 0.36
CCNA2 P20248 1/20 0.34
CDK2 P24941 1/20 0.34
MAP3K14 Q99558 2/20 0.33
KDM4E B2RXH2 2/20 0.33
POLB P06746 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
RAB9A P51151 1/20 0.32
GFER P55789 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7618865 0.81 SMN1; SMN2 (0.50) ALDH1A1SMN1; SMN2KDM4EPOLBMAPT
SCHEMBL31561546 0.79 ALDH1A1 (0.53) ALDH1A1RXFP1NUDT1KDM4EMAPT
SCHEMBL237122 0.79 ALDH1A1 (0.53) ALDH1A1RXFP1NUDT1KDM4EMAPT
SCHEMBL27657809 0.76 ALDH1A1 (0.50) ALDH1A1RXFP1NUDT1FGFR1GFER
SCHEMBL28016408 0.76 ALDH1A1 (0.50) ALDH1A1RXFP1CDK2
SCHEMBL3861922 0.76 SMN1; SMN2 (0.46) ALDH1A1SMN1; SMN2
SCHEMBL1551962 0.76 KDM4E (0.50) ALDH1A1SMN1; SMN2KDM4E
SCHEMBL5034214 0.76 ALDH1A1 (0.50) ALDH1A1RXFP1
SCHEMBL3963577 0.76 ALDH1A1 (0.50) ALDH1A1RXFP1FGFR1MAP3K14KDM4E
SCHEMBL6017103 0.76 ALDH1A1 (0.46) ALDH1A1RXFP1NUDT1FGFR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101451125-A Method for culturing transgene rabbit adult fibroblast cloning embryo INST ANIMAL SCIENCES CAAS (CN) 2009-06-10 CN claimed
CN-110461858-A Acyl nucleosides phosphonate ester, its prodrug and its purposes as drug UNIV MONTPELLIER 2019-11-15 CN disclosed
EP-3328394-A1 CONCATEMERIC PEPTIDE EPITOPE RNAS ModernaTX, Inc. (US) 2018-06-06 EP disclosed
CN-107124889-A Artificial nucleic acid molecules 库瑞瓦格股份公司 2017-09-01 CN disclosed
WO-2017020026-A1 CONCATEMERIC PEPTIDE EPITOPES RNAS MODERNATX, INC. (US) 2017-02-02 WO disclosed
CN-101451125-A Method for culturing transgene rabbit adult fibroblast cloning embryo INST ANIMAL SCIENCES CAAS (CN) 2009-06-10 CN disclosed
EP-0502690-B1 Cyclopropane derivative AJINOMOTO KK (JP) 1999-12-01 EP disclosed
CN-1020107-C Process for preparing antiviral compounds WELLCOME FOUND (GB) 1993-03-17 CN disclosed
EP-0502690-A2 Cyclopropane derivative Ajinomoto Co., Inc. (JP) 1992-09-09 EP disclosed
CN-1031233-A Antiviral compound WELLCOME FOUND (GB) 1989-02-22 CN disclosed