Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734891 | 0.82 | — | — | |
| Pyridine SCHEMBL28193399 | 0.82 | TSHR (0.56) | USP2RAB9ALTA4HMAPK14MAPK10 | |
| Pyridine SCHEMBL27658246 | 0.79 | CYP19A1 (0.39) | RAB9ATSHRNAPRTTDP1KMT2A | |
| SCHEMBL16882937 | 0.75 | BCL2L1 (0.44) | RAB9AMAPK14MAPK10 | |
| Fluorobenzene SCHEMBL27666757 | 0.74 | TSHR (0.53) | USP2RAB9ALTA4HMAPK14MAPK10 | |
| SCHEMBL470271 | 0.71 | — | — | |
| Pyridine SCHEMBL1173460 | 0.70 | TSHR (0.41) | USP2RAB9ALTA4HMAPK14MAPK10 | |
| SCHEMBL29219390 | 0.69 | USP2 (0.50) | USP2RAB9ALTA4HMAPK14MAPK10 | |
| Pyridine SCHEMBL293650 | 0.68 | — | — | |
| Pyridine SCHEMBL28959057 | 0.68 | NAPRT (0.69) | TSHRNAPRTTDP1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972695-A | Treatment or prevention of skin conditions or tissue conditions in animals using boryloxypyridylmethanones | ANACOR PHARMACEUTICALS INC (US) | 2007-05-30 | — | — | CN | disclosed |