Pyridine

Pyridine

SCHEMBL1173460

Fc1ccc(B(c2ccc(F)cc2)c2ccc(F)cc2)cc1.c1ccncc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.41
NAPRT Q6XQN6 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ORAI1 Q96D31 1/20 0.41
ORAI2 Q96SN7 1/20 0.41
ORAI3 Q9BRQ5 1/20 0.41
TRPV6 Q9H1D0 1/20 0.41
USP2 O75604 1/20 0.38
RAB9A P51151 1/20 0.38
LTA4H P09960 1/20 0.38
MAPK14 Q16539 6/20 0.37
MAPK10 P53779 1/20 0.37
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
GCGR P47871 2/20 0.33
MAPK13 O15264 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPK12 P53778 1/20 0.33
MAPK11 Q15759 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL28193399 0.85 TSHR (0.56) TSHRNAPRTTDP1USP2RAB9A
SCHEMBL1265694 0.80 TRPV6 (0.48) TSHRORAI1ORAI2ORAI3TRPV6
SCHEMBL1265686 0.80 TRPV6 (0.48) TSHRORAI1ORAI2ORAI3TRPV6
SCHEMBL6556553 0.80 TRPV6 (0.48) TSHRORAI1ORAI2ORAI3TRPV6
Pyridine SCHEMBL394177 0.80 TSHR (0.50) TSHRNAPRTTDP1ORAI1ORAI2
SCHEMBL125724 0.80 ORAI1 (0.58) ORAI1ORAI2ORAI3TRPV6RAB9A
Pyridine SCHEMBL28276555 0.78 TSHR (0.47) TSHRNAPRTTDP1ORAI1ORAI2
Pyridine SCHEMBL7650859 0.78 TSHR (0.47) TSHRNAPRTTDP1ORAI1ORAI2
Fluorobenzene SCHEMBL27666757 0.78 TSHR (0.53) TSHRNAPRTTDP1USP2RAB9A
Pyridine SCHEMBL1173561 0.77 ORAI1 (0.45) TSHRNAPRTTDP1ORAI1ORAI2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-62277307-A None JP disclosed
US-8436173-B2 Boron compounds, their production processes, and functional electronic devices using same KYOTO UNIVERSITY (JP) 2013-05-07 US disclosed
US-20110046372-A1 NOVEL BORON COMPOUNDS, THEIR PRODUCTION PROCESSES, AND FUNCTIONAL ELECTRONIC DEVICES USING SAME Kyoto University and Nippon Shokubai Co., LTD. 2011-02-24 US disclosed
EP-2233490-A1 NOVEL BORON COMPOUND, METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRONIC DEVICE USING THE SAME Kyoto University (JP) 2010-09-29 EP disclosed
JP-S62277307-A INSECTICIDE CONTAINING BORON COMPOUND SDS BIOTECH KK 1987-12-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110046372-A1 NOVEL BORON COMPOUNDS, THEIR PRODUCTION PROCESSES, AND FUNCTIONAL ELECTRONIC DEVICES USING SAME ETFB, SLC40A1, SLC19A1 TSHR 3575/4885NAPRT 402/4885TDP1 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.