Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972392 | 0.82 | — | — | |
| Pyridine SCHEMBL27657920 | 0.79 | USP2 (0.39) | TSHRNAPRTTDP1KMT2AMEN1 | |
| SCHEMBL20083331 | 0.75 | CYP1A2 (0.48) | TSHRCYP1A2KDM4ELMNAGAA | |
| Chlorobenzene SCHEMBL8412249 | 0.74 | TSHR (0.65) | CYP19A1TSHRNAPRTTDP1CYP1A2 | |
| Chlorobenzene SCHEMBL27844544 | 0.72 | TSHR (0.61) | CYP19A1TSHRNAPRTTDP1CYP1A2 | |
| Chlorobenzene SCHEMBL5317381 | 0.72 | TSHR (0.61) | CYP19A1TSHRNAPRTTDP1RAB9A | |
| SCHEMBL470271 | 0.71 | — | — | |
| 4-Chloroaniline SCHEMBL28179367 | 0.71 | MAOA (0.48) | CYP19A1TSHRNAPRTTDP1KMT2A | |
| Pyridine SCHEMBL11016675 | 0.71 | TSHR (0.43) | CYP19A1TSHRNAPRTTDP1KMT2A | |
| Pyridine SCHEMBL1173561 | 0.70 | ORAI1 (0.45) | CYP19A1TSHRNAPRTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1972695-A | Treatment or prevention of skin conditions or tissue conditions in animals using boryloxypyridylmethanones | ANACOR PHARMACEUTICALS INC (US) | 2007-05-30 | — | — | CN | disclosed |