Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.51 |
| ▸ | MPL | P40238 | 4/20 | 0.46 |
| ▸ | CTRC | Q99895 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ATIC | P31939 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL10614025 | 1.00 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 | |
| SCHEMBL41541 | 0.98 | CYP2D6 (0.53) | CYP2D6CTRB1MPLCTRCCA1 | |
| SCHEMBL4897459 | 0.96 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 | |
| SCHEMBL3233255 | 0.96 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 | |
| Hydrochloric Acid SCHEMBL251599 | 0.96 | CTRB1 (0.55) | CYP2D6CTRB1MPLCTRCCA1 | |
| SCHEMBL3233245 | 0.96 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 | |
| SCHEMBL5077155 | 0.96 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 | |
| Water SCHEMBL669870 | 0.96 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 | |
| SCHEMBL4578484 | 0.96 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 | |
| SCHEMBL4314625 | 0.96 | CYP2D6 (0.51) | CYP2D6CTRB1MPLCTRCCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1950422-A | Binder compositions and associated methods | KNAUF INSULATION GMBH (US) | 2007-04-18 | — | — | CN | claimed |
| CN-105968110-B | Kinase inhibitors | 奇斯药制品公司 | 2018-04-27 | — | — | CN | disclosed |
| CN-105503861-B | Kinase inhibitors | 奇斯药制品公司 | 2017-08-01 | — | — | CN | disclosed |
| CN-105968110-A | Kinase inhibitors | 奇斯药制品公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-103974953-B | Inhibitors of kinases | 奇斯药制品公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-104039787-B | Kinase inhibitors | 奇斯药制品公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-103987708-B | The derivant of 4-hydroxyl-1,2,3,4-naphthane-1-base urea and the purposes in treatment of respiratory diseases thereof | 奇斯药制品公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-105503861-A | Kinase inhibitors | CHIESI FARM SPA | 2016-04-20 | — | — | CN | disclosed |
| CN-105377847-A | Kinase inhibitors | CHIESI FARM SPA | 2016-03-02 | — | — | CN | disclosed |
| CN-105308046-A | Kinase inhibitors | CHIESI FARMA SPA | 2016-02-03 | — | — | CN | disclosed |
| CN-105308044-A | Derivatives of [1, 2, 4]-triazolo-[4, 3-A]-pyridine as p38 MAP kinase inhibitors | CHIESI FARMA SPA | 2016-02-03 | — | — | CN | disclosed |
| CN-104039787-A | Kinase inhibitors | CHIESI FARMA SPA | 2014-09-10 | — | — | CN | disclosed |
| CN-103987708-A | Derivatives of 4-hydroxy-1,2,3,4-tetrahydronaphtalen-1-yl urea and uses thereof in the treatment of diseases of the respiratory tract and other diseases | CHIESI FARMA SPA | 2014-08-13 | — | — | CN | disclosed |
| CN-103974953-A | Kinase inhibitors | CHIESI FARMA SPA | 2014-08-06 | — | — | CN | disclosed |
| CN-103483338-A | Triazolopyridine derivatives as p38 map kinase inhibitors | CHIESI FARMA SPA | 2014-01-01 | — | — | CN | disclosed |
| CN-102395586-A | Triazolopyridine Derivatives as P38MAP Kinase Inhibitors | THERAPEUTICS INFLAMMATION LTD | 2012-03-28 | — | — | CN | disclosed |
| CN-102388025-A | Pyrimidopyridazine derivatives useful as p38 mapk inhibitors | PULMAGEN THERAPEUTICS INFLAMMA | 2012-03-21 | — | — | CN | disclosed |
| CN-101407468-A | Novel method for synthesizing aclatonium napadisilate | YANGZIJIANG PHARMACEUTICAL GRO (CN) | 2009-04-15 | — | — | CN | disclosed |
| CN-101076549-A | Polyester binding compositions | KNAUF INSULATION GMBH (US) | 2007-11-21 | — | — | CN | disclosed |
| CN-1950422-A | Binder compositions and associated methods | KNAUF INSULATION GMBH (US) | 2007-04-18 | — | — | CN | disclosed |