Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2938583 | 0.83 | MEN1 (0.69) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL13815996 | 0.80 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL1553100 | 0.79 | MEN1 (1.00) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL14483300 | 0.78 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10357761 | 0.78 | MEN1 (0.61) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL5067031 | 0.77 | HPGD (0.73) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL28524227 | 0.77 | RAB9A (0.64) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL14482170 | 0.76 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL6070720 | 0.75 | PDE4D (0.68) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL5776434 | 0.75 | POLB (0.48) | MEN1KMT2ASMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1960976-A | 4-carbox pyrazole derivates useful as anti-viral agents | SMITHKLINE BEECHAM CORP (US) | 2007-05-09 | — | — | CN | disclosed |