Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27639564 | 0.89 | PPARG (0.45) | PTPN1ALDH1A1HTTHPGDCYP19A1 | |
| SCHEMBL27660340 | 0.88 | PTGES (0.46) | PTPN1ALOX5PTGES | |
| SCHEMBL10758599 | 0.85 | PTPN1 (0.51) | PTPN1ALDH1A1HTTHPGDCYP19A1 | |
| SCHEMBL9733519 | 0.84 | PTPN1 (0.56) | PTPN1ALOX5MEN1KMT2A | |
| SCHEMBL27639602 | 0.79 | HPGD (0.48) | PTPN1ALDH1A1HTTHPGDCYP19A1 | |
| SCHEMBL3893527 | 0.76 | TSHR (0.66) | ALDH1A1MEN1KMT2APDE4B | |
| SCHEMBL23027375 | 0.75 | CYP19A1 (0.47) | PTPN1ALDH1A1HPGDCYP19A1ALOX5 | |
| SCHEMBL18123531 | 0.75 | CYP19A1 (0.47) | PTPN1ALDH1A1CYP19A1ALOX5PTGES | |
| SCHEMBL6331262 | 0.75 | HTT (0.67) | ALDH1A1HTTMEN1KMT2A | |
| SCHEMBL3303362 | 0.75 | CYP19A1 (0.56) | ALDH1A1HPGDCYP19A1ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | claimed |
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | disclosed |