Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.48 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9349305 | 0.87 | PTPN1 (0.55) | PTPN1KDM4EALOX5GABRA1GABRB2 | |
| SCHEMBL4982250 | 0.86 | PTPN1 (0.60) | PTPN1KDM4EALOX5GABRA1GABRB2 | |
| SCHEMBL4981784 | 0.85 | ALDH1A1 (0.61) | PTPN1ALOX5PTGS1MEN1KMT2A | |
| SCHEMBL27660352 | 0.84 | PTPN1 (0.54) | PTPN1ALOX5MEN1KMT2A | |
| SCHEMBL3542900 | 0.84 | PTPN1 (0.57) | PTPN1ALOX5GABRA1GABRB2CNR2 | |
| SCHEMBL9417984 | 0.82 | CNR2 (0.53) | KDM4ECNR2MAPTL3MBTL1 | |
| SCHEMBL9417845 | 0.82 | CNR2 (0.50) | KDM4ECNR2L3MBTL1 | |
| SCHEMBL9734673 | 0.82 | PTGDR (0.45) | PTPN1KDM4EELANEMAPTMEN1 | |
| SCHEMBL9417760 | 0.82 | KDM4E (0.50) | KDM4ECNR2ELANEMAPTMEN1 | |
| SCHEMBL4979459 | 0.82 | HSP90AA1 (0.58) | PTPN1KDM4EALOX5GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661738-B | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2023-01-10 | — | — | CN | disclosed |
| CN-112661738-A | Flavanone compound and preparation method and application thereof | 南方医科大学 | 2021-04-16 | — | — | CN | disclosed |
| US-5098613-A | Aromatic ethers for treatment of mammals | ELI LILLY AND COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-4945099-A | LEUKOTRIENE ANTAGONIST | ELI LILLY AND COMPANY (US) | 1990-07-31 | — | — | US | disclosed |
| EP-0276065-B1 | ANTI-INFLAMMATORY AGENTS | ELI LILLY AND COMPANY (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0276065-A1 | Anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |