Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Demannose. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Galactose SCHEMBL10596615 | 1.00 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Galactose SCHEMBL9726398 | 1.00 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL30410784 | 1.00 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL5471738 | 1.00 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL27429235 | 1.00 | PDE4A (0.50) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL20603115 | 0.98 | PDE4A (0.48) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL27552648 | 0.98 | PDE4A (0.48) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL18886543 | 0.98 | PDE4A (0.48) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL3935927 | 0.96 | PDE4A (0.47) | PDE4AUSP2SLCO1B1LMNATP53 | |
| Demannose SCHEMBL6343864 | 0.95 | PDE4A (0.46) | PDE4AUSP2SLCO1B1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109715783-A | Method for producing lactic acid | 隐花果乳酸有限责任公司 | 2019-05-03 | — | — | CN | claimed |
| CN-220872482-U | Glucose lactic acid analyzer that practicality is strong | 美德太平洋（天津）生物科技股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-220872482-U | Glucose lactic acid analyzer that practicality is strong | 美德太平洋（天津）生物科技股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-111315861-A | System for cell enrichment by cross-flow filtration | 通用电气公司 | 2020-06-19 | — | — | CN | disclosed |
| CN-110709385-A | Haloallylamine pyrazole derivative inhibitors of lysyl oxidase and uses thereof | 法玛西斯有限公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-209311453-U | A kind of combined type multiple groups POCT glucose lactic acid analysis instrument | 美德太平洋（天津）生物科技股份有限公司 | 2019-08-27 | — | — | CN | disclosed |
| CN-209014580-U | A kind of bed that stability is strong side real-time test POCT glucose lactic acid analysis instrument | 美德太平洋（天津）生物科技股份有限公司 | 2019-06-21 | — | — | CN | disclosed |
| CN-109906270-A | Genetically modified lactic acid consumption yeast and the zymotechnique using such genetically modified yeast | 嘉吉公司 | 2019-06-18 | — | — | CN | disclosed |
| CN-208520881-U | A kind of other real-time test POCT glucose lactic acid analysis instrument | 美德太平洋（天津）生物科技股份有限公司 | 2019-02-19 | — | — | CN | disclosed |
| CN-107561018-A | A kind of method of glucose or glucose polymer content in measure compound preparation | 华仁药业股份有限公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-103597087-B | Preparation method of butyric acid, butanol and butyl ester | 财团法人工业技术研究院 | 2017-08-04 | — | — | CN | disclosed |
| CN-104207144-B | A kind of many polymerizers of high energy type enteral nutrition | 上海励成营养产品科技股份有限公司 | 2016-09-14 | — | — | CN | disclosed |
| CN-1914332-A | Assay for the identification of microorganisms | RAPID LAB MICROSYSTEMS INC (CA) | 2007-02-14 | — | — | CN | disclosed |